I made a number of transfers before starting the career to keep things fresh. I tried to not make too many transfers for one team but made transfers that have either been rumored or they happened in my FM save and I thought they worked well. This career is starting a year into the future so new teams are in the European competitions and new relegated/promoted sides. Of course I picked Spurs to finish 4th this season so we are in the CL.
England's European sides
Champions League: City, Liverpool, Chelsea, Spurs
Europa League: Arsenal, Man United
Europa Conference: West Ham
Key transfers made;
Departures
Aubameyang to Barca
Lacazette to Atletico Madrid
Xhaka to Roma
Kolasinac, Leno, Mari out
Arrivals
Ruben Neves
Alexander Isak
Bruno Guimaraes
Sam Johnstone
Ryan Nyambe
Saliba (back from loan)
Aston Villa
Arrivals
Dele Alli
Philippe Coutinho
Lucas Digne
Fulham - promoted
Arrivals
James Milner
Leicester City
Departures
James Maddison
Arrivals
Donny van de Beek
Liverpool
Departures
James Milner
Ox
Arrivals
James Maddison
Ismail Sarr
Man City
Arrivals
Erling Haaland
Man United
Departures
Dean Henderson
Arrivals
Yves Bissouma
Newcastle United - money takeover
Arrivals
Georginio Wijnaldum
Kieran Trippier
Chris Wood
Dean Henderson
Dusan Vlahovic
Sven Botman
Ousmane Dembele
QPR - promoted
Arrivals
Ben Mee
James Tarkowski
Emil Krafth
Takumi Minamino
Tottenham
Departures
Ndombele to OL
Lo Celso to Atletico
Dele Alli to Aston Villa
Arrivals
Christian Eriksen
Lorenzo Pellegrini
Emmanuel Dennis
Nikola Milenkovic
West Ham
Arrivals
Antony Martial